Utility Values Used in National Institute for Health and Care Excellence (NICE) Technology Appraisals of Medicines for 4 Metastatic Cancers

National Institute for Health and Care Excellence.

The National Institute for Clinical Excellence (NICE).

In discussions on the development of the institutional framework for decisions on the benefit package of social health insurance in Germany, the English National Institute for Clinical Excellence (NICE) is considered as either a good or a bad example for reform. According to this study, the procedures and criteria applied by NICE for making health care coverage decisions are legitimate. Procedu...

Simulation contact lenses for AMD health state utility values in NICE appraisals: a different reality

BACKGROUND/AIMS The National Institute for Health and Care Excellence (NICE) has recommended the use of ranibizumab for neovascular age-related macular degeneration (AMD) and for diabetic macular oedema (DMO) as part of its health technology appraisal process. In the economic evaluations of both interventions, utility values were derived from members of the general public wearing contact lenses...

Managing Conflicts of Interest in the UK National Institute for Health and Care Excellence (NICE) Clinical Guidelines Programme: Qualitative Study

BACKGROUND There is international concern that conflicts of interest (COI) may bias clinical guideline development and render it untrustworthy. Guideline COI policies exist with the aim of reducing this bias but it is not known how such policies are interpreted and used by guideline producing organisations. This study sought to determine how conflicts of interest (COIs) are disclosed and manage...

National Institute for Health and Clinical Excellence (NICE) guideline: psychosis with coexisting substance misuse.

This editorial summarizes the main recommendations of the NICE guideline on psychosis and coexisting substance misuse. It outlines the dearth of specific evidence (especially for integrated models), but emphasizes implementation of evidence for the treatment of psychosis and substance misuse separately for current best practice and policy. It highlights research options and training needs to fu...